DEV CONCEPT
FOR SCIENTISTS AND PATHOLOGY LABORATORIES No charge to approved accounts
CR-GNB
CARBAPENEM-RESISTANT GRAM-NEGATIVES
Link · a Clinigen company
Complete two-test pack

What a laboratory needs on the bench

These are the consumables that are not already sitting in a standard Australian micro lab (plates, loops, incubators, MALDI). Order only what you do not already hold. Automated instruments and GeneXpert cartridges are out of scope for this pack.

Test 1 · enzyme ID

Carbapenemase 5-plex lateral flow

Immunochromatographic cassette used on a cultured isolate. Reports KPC, NDM, VIM, IMP and OXA-48-like as separate lines in about 15 minutes. No analyser. Room-temperature storage. Typical pack: 20 tests.

Test 2 · screen

Siderophore cephalosporin AST disk 30 µg

Kirby-Bauer disk for aerobic Gram-negatives on standard Mueller-Hinton agar. Do not iron-deplete the plate. Read zone diameter against current EUCAST or CLSI tables. Everyday first method.

Test 2 · confirm

Siderophore cephalosporin BMD panel

Compact broth microdilution panel with the dried agent in doubling dilutions and tubes of iron-depleted cation-adjusted Mueller-Hinton broth. Use when the disk is in a technical grey zone or a MIC in mg/L must be reported.

Quality control

Reference Gram-negative strains

Lyophilised E. coli and P. aeruginosa QC strains with published zone and MIC ranges for the disk and BMD methods. Required for NATA method verification and routine QC.

Suggested starter quantities

LineSKUPackTypical first order
Carbapenemase 5-plex LFACARBA5-2020 cassettes1 box
Siderophore cephalosporin disk 30 µgFDC30-5050 disks1 cartridge
Siderophore cephalosporin BMDCOMASP-88 MIC tests + ID-CAMHB1 kit
QC strain setQC-GN-SET2–3 strains1 set

Labs already hold MH agar, McFarland standards and incubators. Those are not supplied. Chromogenic CRE agar and PCR are optional and not part of this pack.

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